Regulation of the Yeast Yap1p Nuclear Export Signal Is Mediated by Redox Signal-Induced Reversible Disulfide Bond Formation

Yap1p, a crucial transcription factor in the oxidative stress response of Saccharomyces cerevisiae, is transported in and out of the nucleus under nonstress conditions. The nuclear export step is specifically inhibited by H(2)O(2) or the thiol oxidant diamide, resulting in Yap1p nuclear accumulation...

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Detalhes bibliográficos
Main Authors: Kuge, Shusuke, Arita, Minetaro, Murayama, Asako, Maeta, Kazuhiro, Izawa, Shingo, Inoue, Yoshiharu, Nomoto, Akio
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Nucleocytoplasmic Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87331/
https://ncbi.nlm.nih.gov/pubmed/11509657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6139-6150.2001
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