The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3

Repression of gene transcription is linked to regulation of chromatin structure through deacetylation of core histone amino-terminal tails. This action is mediated by histone deacetylases (HDACs) that function within active multiprotein complexes directed to the promoters of repressed genes. In vivo...

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Bibliographic Details
Main Authors: Guenther, Matthew G., Barak, Orr, Lazar, Mitchell A.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2001
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC87326/
https://ncbi.nlm.nih.gov/pubmed/11509652
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.18.6091-6101.2001
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