The SMRT and N-CoR Corepressors Are Activating Cofactors for Histone Deacetylase 3

Repression of gene transcription is linked to regulation of chromatin structure through deacetylation of core histone amino-terminal tails. This action is mediated by histone deacetylases (HDACs) that function within active multiprotein complexes directed to the promoters of repressed genes. In vivo...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Guenther, Matthew G., Barak, Orr, Lazar, Mitchell A.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2001
Assuntos:	Transcriptional Regulation
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87326/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11509652/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.18.6091-6101.2001
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