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HERP, a Novel Heterodimer Partner of HES/E(spl) in Notch Signaling

HERP1 and -2 are members of a new basic helix-loop-helix (bHLH) protein family closely related to HES/E(spl), the only previously known Notch effector. Like that of HES, HERP mRNA expression is directly up-regulated by Notch ligand binding without de novo protein synthesis. HES and HERP are individu...

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Bibliografiske detaljer
Main Authors: Iso, Tatsuya, Sartorelli, Vittorio, Poizat, Coralie, Iezzi, Simona, Wu, Hung-Yi, Chung, Gene, Kedes, Larry, Hamamori, Yasuo
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC87325/
https://ncbi.nlm.nih.gov/pubmed/11486045
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.6080-6089.2001
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