Mre11 Complex and DNA Replication: Linkage to E2F and Sites of DNA Synthesis

We show that the Mre11 complex associates with E2F family members via the Nbs1 N terminus. This association and Nbs1 phosphorylation are correlated with S-phase checkpoint proficiency, whereas neither is sufficient individually for checkpoint activation. The Nbs1 E2F interaction occurred near the Ep...

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Hlavní autoři: Maser, Richard S., Mirzoeva, Olga K., Wells, Julie, Olivares, Heidi, Williams, Bret R., Zinkel, Robert A., Farnham, Peggy J., Petrini, John H. J.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
DNA Dynamics and Chromosome Structure
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC87318/
https://ncbi.nlm.nih.gov/pubmed/11486038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.6006-6016.2001
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