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Mre11 Complex and DNA Replication: Linkage to E2F and Sites of DNA Synthesis
We show that the Mre11 complex associates with E2F family members via the Nbs1 N terminus. This association and Nbs1 phosphorylation are correlated with S-phase checkpoint proficiency, whereas neither is sufficient individually for checkpoint activation. The Nbs1 E2F interaction occurred near the Ep...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Microbiology
2001
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87318/ https://ncbi.nlm.nih.gov/pubmed/11486038 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.17.6006-6016.2001 |
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