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Histone Deacetylase 4 Possesses Intrinsic Nuclear Import and Export Signals

Nucleocytoplasmic trafficking of histone deacetylase 4 (HDAC4) plays an important role in regulating its function, and binding of 14-3-3 proteins is necessary for its cytoplasmic retention. Here, we report the identification of nuclear import and export sequences of HDAC4. While its N-terminal 118 r...

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Udgivet i:Mol Cell Biol
Principais autores: Wang, Audrey H., Yang, Xiang-Jiao
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2001
Fag:
Nucleocytoplasmic Communication
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87317/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11486037/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.17.5992-6005.2001
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