Overlapping Functions of the pRb Family in the Regulation of rRNA Synthesis

The “pocket” proteins pRb, p107, and p130 are a family of negative growth regulators. Previous studies have demonstrated that overexpression of pRb can repress transcription by RNA polymerase (Pol) I. To assess whether pRb performs this role under physiological conditions, we have examined pre-rRNA...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Ciarmatori, Sonia, Scott, Pamela H., Sutcliffe, Josephine E., McLees, Angela, Alzuherri, Hadi M., Dannenberg, Jan-Hermen, te Riele, Hein, Grummt, Ingrid, Voit, Renate, White, Robert J.
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2001
Schlagworte:	Transcriptional Regulation
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87300/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11486020/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.17.5806-5814.2001
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Overlapping Functions of the pRb Family in the Regulation of rRNA Synthesis

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