Disruption of γ-Glutamyl Leukotrienase Results in Disruption of Leukotriene D(4) Synthesis In Vivo and Attenuation of the Acute Inflammatory Response

To study the function of γ-glutamyl leukotrienase (GGL), a newly identified member of the γ-glutamyl transpeptidase (GGT) family, we generated null mutations in GGL (GGL(tm1)) and in both GGL and GGT (GGL(tm1)-GGT(tm1)) by a serial targeting strategy using embryonic stem cells. Mice homozygous for G...

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Bibliografiske detaljer

Udgivet i:	Mol Cell Biol
Principais autores:	Shi, Zheng-Zheng, Han, Bing, Habib, Geetha M., Matzuk, Martin M., Lieberman, Michael W.
Format:	Artigo
Sprog:	Inglês
Udgivet:	Taylor & Francis 2001
Fag:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87261/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11463821/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.16.5389-5395.2001
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