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Disruption of γ-Glutamyl Leukotrienase Results in Disruption of Leukotriene D(4) Synthesis In Vivo and Attenuation of the Acute Inflammatory Response
To study the function of γ-glutamyl leukotrienase (GGL), a newly identified member of the γ-glutamyl transpeptidase (GGT) family, we generated null mutations in GGL (GGL(tm1)) and in both GGL and GGT (GGL(tm1)-GGT(tm1)) by a serial targeting strategy using embryonic stem cells. Mice homozygous for G...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC87261/ https://ncbi.nlm.nih.gov/pubmed/11463821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.16.5389-5395.2001 |
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