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exo1-Dependent Mutator Mutations: Model System for Studying Functional Interactions in Mismatch Repair

EXO1 interacts with MSH2 and MLH1 and has been proposed to be a redundant exonuclease that functions in mismatch repair (MMR). To better understand the role of EXO1 in mismatch repair, a genetic screen was performed to identify mutations that increase the mutation rates caused by weak mutator mutati...

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Hlavní autoři: Amin, Neelam S., Nguyen, My-Nga, Oh, Scott, Kolodner, Richard D.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC87239/
https://ncbi.nlm.nih.gov/pubmed/11438669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.5142-5155.2001
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