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Linking the 3′ Poly(A) Tail to the Subunit Joining Step of Translation Initiation: Relations of Pab1p, Eukaryotic Translation Initiation Factor 5B (Fun12p), and Ski2p-Slh1p

The 3′ poly(A) structure improves translation of a eukaryotic mRNA by 50-fold in vivo. This enhancement has been suggested to be due to an interaction of the poly(A) binding protein, Pab1p, with eukaryotic translation initiation factor 4G (eIF4G). However, we find that mutation of eIF4G eliminating...

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Main Authors: Searfoss, Anjanette, Dever, Thomas E., Wickner, Reed
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2001
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC87206/
https://ncbi.nlm.nih.gov/pubmed/11438647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.15.4900-4908.2001
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