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Cell-Specific Association and Shuttling of IκBα Provides a Mechanism for Nuclear NF-κB in B Lymphocytes

Mature B lymphocytes are unique in containing nuclear Rel proteins prior to cell stimulation. This activity consists largely of p50–c-Rel heterodimers, and its importance for B-cell function is exemplified by reduced B-cell viability in several genetically altered mouse strains. Here we suggest a me...

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Hlavní autoři: Tam, Winnie F., Wang, Weihong, Sen, Ranjan
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2001
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC87179/
https://ncbi.nlm.nih.gov/pubmed/11416157
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.14.4837-4846.2001
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