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Postrepression Activation of NF-κB Requires the Amino-Terminal Nuclear Export Signal Specific to IκBα

One of the most prominent NF-κB target genes in mammalian cells is the gene encoding one of its inhibitor proteins, IκBα. The increased synthesis of IκBα leads to postinduction repression of nuclear NF-κB activity. However, it is unknown why IκBα, among multiple IκB family members, is involved in th...

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Detalhes bibliográficos
Main Authors: Huang, Tony T., Miyamoto, Shigeki
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC87155/
https://ncbi.nlm.nih.gov/pubmed/11416149
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.14.4737-4747.2001
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