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The Corepressor mSin3a Interacts with the Proline-Rich Domain of p53 and Protects p53 from Proteasome-Mediated Degradation

While the transactivation function of the tumor suppressor p53 is well understood, less is known about the transrepression functions of this protein. We have previously shown that p53 interacts with the corepressor protein mSin3a (hereafter designated Sin3) in vivo and that this interaction is criti...

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Publicat a:Mol Cell Biol
Autors principals: Zilfou, Jack T., Hoffman, William H., Sank, Michael, George, Donna L., Murphy, Maureen
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2001
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Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC87060/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11359905/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.12.3974-3985.2001
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