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A Conserved Cyclin-Binding Domain Determines Functional Interplay between Anaphase-Promoting Complex–Cdh1 and Cyclin A-Cdk2 during Cell Cycle Progression

Periodic activity of the anaphase-promoting complex (APC) ubiquitin ligase determines progression through multiple cell cycle transitions by targeting cell cycle regulators for destruction. At the G(1)/S transition, phosphorylation-dependent dissociation of the Cdh1-activating subunit inhibits the A...

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Main Authors: Sørensen, Claus Storgaard, Lukas, Claudia, Kramer, Edgar R., Peters, Jan-Michael, Bartek, Jiri, Lukas, Jiri
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC87003/
https://ncbi.nlm.nih.gov/pubmed/11340163
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.11.3692-3703.2001
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