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Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization.

Cyclin-dependent kinases (CDKs) are essential for regulating key transitions in the cell cycle, including initiation of DNA replication, mitosis and prevention of re-replication. Here we demonstrate that mammalian CDC6, an essential regulator of initiation of DNA replication, is phosphorylated by CD...

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Main Authors: Petersen, B O, Lukas, J, Sørensen, C S, Bartek, J, Helin, K
格式: Artigo
語言:Inglês
出版: 1999
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1171134/
https://ncbi.nlm.nih.gov/pubmed/9889196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.2.396
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