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Phosphorylation of mammalian CDC6 by cyclin A/CDK2 regulates its subcellular localization.
Cyclin-dependent kinases (CDKs) are essential for regulating key transitions in the cell cycle, including initiation of DNA replication, mitosis and prevention of re-replication. Here we demonstrate that mammalian CDC6, an essential regulator of initiation of DNA replication, is phosphorylated by CD...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1171134/ https://ncbi.nlm.nih.gov/pubmed/9889196 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/18.2.396 |
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