Chromosome Instability and Defective Recombinational Repair in Knockout Mutants of the Five Rad51 Paralogs

The Rad51 protein, a eukaryotic homologue of Escherichia coli RecA, plays a central role in both mitotic and meiotic homologous DNA recombination (HR) in Saccharomyces cerevisiae and is essential for the proliferation of vertebrate cells. Five vertebrate genes, RAD51B, -C, and -D and XRCC2 and -3, a...

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Autores principales: Takata, Minoru, Sasaki, Masao S., Tachiiri, Seiji, Fukushima, Toru, Sonoda, Eiichiro, Schild, David, Thompson, Larry H., Takeda, Shunichi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2001
Materias:
DNA Dynamics and Chromosome Structure
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC86915/
https://ncbi.nlm.nih.gov/pubmed/11283264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2858-2866.2001
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