The Essential Functions of Human Rad51 Are Independent of ATP Hydrolysis

Genetic recombination and the repair of double-strand DNA breaks in Saccharomyces cerevisiae require Rad51, a homologue of the Escherichia coli RecA protein. In vitro, Rad51 binds DNA to form an extended nucleoprotein filament and catalyzes the ATP-dependent exchange of DNA between molecules with ho...

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Detalhes bibliográficos
Main Authors: Morrison, Ciaran, Shinohara, Akira, Sonoda, Eiichiro, Yamaguchi-Iwai, Yuko, Takata, Minoru, Weichselbaum, Ralph R., Takeda, Shunichi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 1999
Assuntos:
DNA Dynamics and Chromosome Structure
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC84684/
https://ncbi.nlm.nih.gov/pubmed/10490626
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