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S and G(2) Phase Roles for Cdk2 Revealed by Inducible Expression of a Dominant-Negative Mutant in Human Cells

Cyclin-dependent kinase 2 (Cdk2) is essential for initiation of DNA synthesis in higher eukaryotes. Biochemical studies in Xenopus egg extracts and microinjection studies in human cells have suggested an additional function for Cdk2 in activation of Cdk1 and entry into mitosis. To further examine th...

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Detaylı Bibliyografya
Asıl Yazarlar: Hu, Bing, Mitra, Jayashree, van den Heuvel, Sander, Enders, Greg H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2001
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC86906/
https://ncbi.nlm.nih.gov/pubmed/11283255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2755-2766.2001
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