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Sustained Signaling by Phospholipase C-γ Mediates Nerve Growth Factor-Triggered Gene Expression

In contrast to conventional signaling by growth factors that requires their continual presence, a 1-min pulse of nerve growth factor (NGF) is sufficient to induce electrical excitability in PC12 cells due to induction of the peripheral nerve type 1 (PN1) sodium channel gene. We have investigated the...

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Autors principals: Choi, Deog-Young, Toledo-Aral, Juan Jose, Segal, Rosalind, Halegoua, Simon
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86900/
https://ncbi.nlm.nih.gov/pubmed/11283249
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2695-2705.2001
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