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Sustained Signaling by Phospholipase C-γ Mediates Nerve Growth Factor-Triggered Gene Expression
In contrast to conventional signaling by growth factors that requires their continual presence, a 1-min pulse of nerve growth factor (NGF) is sufficient to induce electrical excitability in PC12 cells due to induction of the peripheral nerve type 1 (PN1) sodium channel gene. We have investigated the...
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Main Authors: | , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
American Society for Microbiology
2001
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86900/ https://ncbi.nlm.nih.gov/pubmed/11283249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.8.2695-2705.2001 |
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