S338 Phosphorylation of Raf-1 Is Independent of Phosphatidylinositol 3-Kinase and Pak3

The Raf-1 serine/threonine protein kinase requires phosphorylation of the serine at position 338 (S338) for activation. Ras is required to recruit Raf-1 to the plasma membrane, which is where S338 phosphorylation occurs. The recent suggestion that Pak3 could stimulate Raf-1 activity by directly phos...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Chiloeches, Antonio, Mason, Clive S., Marais, Richard
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Cell Growth and Development
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86875/
https://ncbi.nlm.nih.gov/pubmed/11259591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.7.2423-2434.2001
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