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Activation of Akt (Protein Kinase B) in Mammary Epithelium Provides a Critical Cell Survival Signal Required for Tumor Progression
Activation of Akt by the phosphatidylinositol 3′-OH kinase (PI3K) results in the inhibition of proapoptotic signals and the promotion of survival signals (L. P. Kane et al., Curr. Biol. 9:601–604, 1999; G. J. Kops et al., Nature 398:630–634, 1999). Evidence supporting the importance of the PI3K/Akt...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86854/ https://ncbi.nlm.nih.gov/pubmed/11238953 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.6.2203-2212.2001 |
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