ATF4 Degradation Relies on a Phosphorylation-Dependent Interaction with the SCF(βTrCP) Ubiquitin Ligase

The ubiquitin-proteasome pathway regulates gene expression through protein degradation. Here we show that the F-box protein βTrCP, the receptor component of the SCF E3 ubiquitin ligase responsible for IκBα and β-catenin degradation, is colocalized in the nucleus with ATF4, a member of the ATF-CREB b...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Lassot, Irina, Ségéral, Emmanuel, Berlioz-Torrent, Clarisse, Durand, Herve, Groussin, Lionel, Hai, Tsonwin, Benarous, Richard, Margottin-Goguet, Florence
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86853/
https://ncbi.nlm.nih.gov/pubmed/11238952
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.6.2192-2202.2001
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker