β(3)A-Integrin Downregulates the Urokinase-Type Plasminogen Activator Receptor (u-PAR) through a PEA3/ets Transcriptional Silencing Element in the u-PAR Promoter

Migration of cells requires interactions with the extracellular matrix mediated, in part, by integrins, proteases, and their receptors. Previous studies have shown that β(3)-integrin interacts with the urokinase-type plasminogen activator receptor (u-PAR) at the cell surface. Since integrins mediate...

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Autors principals: Hapke, Sandra, Gawaz, Meinrad, Dehne, Kerstin, Köhler, Jenny, Marshall, John F., Graeff, Henner, Schmitt, Manfred, Reuning, Ute, Lengyel, Ernst
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86830/
https://ncbi.nlm.nih.gov/pubmed/11238946
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.6.2118-2132.2001
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