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Switch in 3′ Splice Site Recognition between Exon Definition and Splicing Catalysis Is Important for Sex-lethal Autoregulation

Maintenance of female sexual identity in Drosophila melanogaster involves an autoregulatory loop in which the protein Sex-lethal (SXL) promotes skipping of exon 3 from its own pre-mRNA. We have used transient transfection of Drosophila Schneider cells to analyze the role of exon 3 splice sites in re...

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Pubblicato in:Mol Cell Biol
Autori principali: Penalva, Luiz O. F., Lallena, Maria José, Valcárcel, Juan
Natura: Artigo
Lingua:Inglês
Pubblicazione: Taylor & Francis 2001
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Accesso online:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86793/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238934/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.6.1986-1996.2001
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