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Switch in 3′ Splice Site Recognition between Exon Definition and Splicing Catalysis Is Important for Sex-lethal Autoregulation

Maintenance of female sexual identity in Drosophila melanogaster involves an autoregulatory loop in which the protein Sex-lethal (SXL) promotes skipping of exon 3 from its own pre-mRNA. We have used transient transfection of Drosophila Schneider cells to analyze the role of exon 3 splice sites in re...

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Detalhes bibliográficos
Main Authors: Penalva, Luiz O. F., Lallena, Maria José, Valcárcel, Juan
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86793/
https://ncbi.nlm.nih.gov/pubmed/11238934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.6.1986-1996.2001
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