IκB Kinase-Dependent Chronic Activation of NF-κB Is Necessary for p21(WAF1/Cip1) Inhibition of Differentiation-Induced Apoptosis of Monocytes

The molecular mechanisms regulating monocyte differentiation to macrophages remain unknown. Although the transcription factor NF-κB participates in multiple cell functions, its role in cell differentiation is ill defined. Since differentiated macrophages, in contrast to cycling monocytes, contain si...

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Библиографические подробности
Главные авторы: Pennington, Kevin N., Taylor, Julie A., Bren, Gary D., Paya, Carlos V.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2001
Предметы:
Cell Growth and Development
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC86780/
https://ncbi.nlm.nih.gov/pubmed/11238929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.6.1930-1941.2001
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