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Coordinated Regulation of Rap1 and Thyroid Differentiation by Cyclic AMP and Protein Kinase A
Originally identified as an antagonist of Ras action, Rap1 exhibits many Ras-independent effects, including a role in signaling pathways initiated by cyclic AMP (cAMP). Since cAMP is a critical mediator of the effects of thyrotropin (TSH) on cell proliferation and differentiation, we examined the re...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology
2001
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86776/ https://ncbi.nlm.nih.gov/pubmed/11238928 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.6.1921-1929.2001 |
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