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Coordinated Regulation of Rap1 and Thyroid Differentiation by Cyclic AMP and Protein Kinase A

Originally identified as an antagonist of Ras action, Rap1 exhibits many Ras-independent effects, including a role in signaling pathways initiated by cyclic AMP (cAMP). Since cAMP is a critical mediator of the effects of thyrotropin (TSH) on cell proliferation and differentiation, we examined the re...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Tsygankova, Oxana M., Saavedra, Arturo, Rebhun, John F., Quilliam, Lawrence A., Meinkoth, Judy L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86776/
https://ncbi.nlm.nih.gov/pubmed/11238928
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.6.1921-1929.2001
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