Essential Role of STAT3 in the Control of the Acute-Phase Response as Revealed by Inducible Gene Activation in the Liver

We generated mice carrying a STAT3 allele amenable to Cre-mediated deletion and intercrossed them with Mx-Cre transgenic mice, in which the expression of Cre recombinase can be induced by type I interferon. Interferon-induced deletion of STAT3 occurred very efficiently (more than 90%) in the liver a...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Alonzi, Tonino, Maritano, Diego, Gorgoni, Barbara, Rizzuto, Gabriella, Libert, Claude, Poli, Valeria
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2001
Sujets:	Cell Growth and Development
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86708/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238899/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.5.1621-1632.2001
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