Essential Role of STAT3 in the Control of the Acute-Phase Response as Revealed by Inducible Gene Activation in the Liver

We generated mice carrying a STAT3 allele amenable to Cre-mediated deletion and intercrossed them with Mx-Cre transgenic mice, in which the expression of Cre recombinase can be induced by type I interferon. Interferon-induced deletion of STAT3 occurred very efficiently (more than 90%) in the liver a...

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Bibliografiske detaljer
Main Authors: Alonzi, Tonino, Maritano, Diego, Gorgoni, Barbara, Rizzuto, Gabriella, Libert, Claude, Poli, Valeria
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86708/
https://ncbi.nlm.nih.gov/pubmed/11238899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1621-1632.2001
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