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SH2-B and APS Are Multimeric Adapters That Augment TrkA Signaling

Neurotrophins influence growth and survival of sympathetic and sensory neurons through activation of their receptors, Trk receptor tyrosine kinases. Previously, we identified Src homology 2-B (SH2-B) and APS, which are structurally similar adapter proteins, as substrates of Trk kinases. In the prese...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Qian, Xiaozhong, Ginty, David D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2001
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86707/
https://ncbi.nlm.nih.gov/pubmed/11238898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1613-1620.2001
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