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SH2-B and APS Are Multimeric Adapters That Augment TrkA Signaling

Neurotrophins influence growth and survival of sympathetic and sensory neurons through activation of their receptors, Trk receptor tyrosine kinases. Previously, we identified Src homology 2-B (SH2-B) and APS, which are structurally similar adapter proteins, as substrates of Trk kinases. In the prese...

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Detalhes bibliográficos
Main Authors: Qian, Xiaozhong, Ginty, David D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86707/
https://ncbi.nlm.nih.gov/pubmed/11238898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1613-1620.2001
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