The B Lymphocyte-Specific Coactivator BOB.1/OBF.1 Is Required at Multiple Stages of B-Cell Development

The transcriptional coactivator BOB.1/OBF.1 confers B-cell specificity on the transcription factors Oct1 and Oct2 at octamer site-containing promoters. A hallmark of the BOB.1/OBF.1 mutation in the mouse is the absence of germinal center development in secondary lymphoid organs, demonstrating the re...

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Autors principals: Hess, Jochen, Nielsen, Peter J., Fischer, Klaus-Dieter, Bujard, Hermann, Wirth, Thomas
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Transcriptional Regulation
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86699/
https://ncbi.nlm.nih.gov/pubmed/11238890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1531-1539.2001
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