Roles of the Mitotic Inhibitors Wee1 and Mik1 in the G(2) DNA Damage and Replication Checkpoints

The G(2) DNA damage and DNA replication checkpoints in many organisms act through the inhibitory phosphorylation of Cdc2 on tyrosine-15. This phosphorylation is catalyzed by the Wee1/Mik1 family of kinases. However, the in vivo role of these kinases in checkpoint regulation has been unclear. We show...

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Veröffentlicht in:	Mol Cell Biol
Hauptverfasser:	Rhind, Nicholas, Russell, Paul
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Taylor & Francis 2001
Schlagworte:	Cell Growth and Development
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86696/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238887/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.5.1499-1508.2001
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