Autoinhibition Mechanism of Proto-Dbl
The dbl oncogene encodes a prototype member of the Rho GTPase guanine nucleotide exchange factor (GEF) family. Oncogenic activation of proto-Dbl occurs through truncation of the N-terminal 497 residues. The C-terminal half of proto-Dbl includes residues 498 to 680 and 710 to 815, which fold into the...
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| Published in: | Mol Cell Biol |
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| Main Authors: | , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Taylor & Francis
2001
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86692/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11238883/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.5.1463-1474.2001 |
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