Autoinhibition Mechanism of Proto-Dbl

The dbl oncogene encodes a prototype member of the Rho GTPase guanine nucleotide exchange factor (GEF) family. Oncogenic activation of proto-Dbl occurs through truncation of the N-terminal 497 residues. The C-terminal half of proto-Dbl includes residues 498 to 680 and 710 to 815, which fold into the...

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Autors principals: Bi, Feng, Debreceni, Balazs, Zhu, Kejin, Salani, Barbara, Eva, Alessandra, Zheng, Yi
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2001
Matèries:
Cell Growth and Development
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC86692/
https://ncbi.nlm.nih.gov/pubmed/11238883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.5.1463-1474.2001
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