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Trypanosome RNA Editing: Simple Guide RNA Features Enhance U Deletion 100-Fold
Trypanosome RNA editing is a massive processing of mRNA by U deletion and U insertion, directed by trans-acting guide RNAs (gRNAs). A U deletion cycle and a U insertion cycle have been reproduced in vitro using synthetic ATPase (A6) pre-mRNA and gRNA. Here we examine which gRNA features are importan...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society for Microbiology
2001
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC86679/ https://ncbi.nlm.nih.gov/pubmed/11154275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.3.884-892.2001 |
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