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Trypanosome RNA Editing: Simple Guide RNA Features Enhance U Deletion 100-Fold

Trypanosome RNA editing is a massive processing of mRNA by U deletion and U insertion, directed by trans-acting guide RNAs (gRNAs). A U deletion cycle and a U insertion cycle have been reproduced in vitro using synthetic ATPase (A6) pre-mRNA and gRNA. Here we examine which gRNA features are importan...

Ausführliche Beschreibung

Gespeichert in:
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Cruz-Reyes, Jorge, Zhelonkina, Alevtina, Rusche, Laura, Sollner-Webb, Barbara
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2001
Schlagworte:
Gene Expression
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86679/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154275/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.884-892.2001
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