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Multifaceted Regulation of Cell Cycle Progression by Estrogen: Regulation of Cdk Inhibitors and Cdc25A Independent of Cyclin D1-Cdk4 Function

Estrogens induce proliferation of estrogen receptor (ER)-positive MCF-7 breast cancer cells by stimulating G(1)/S transition associated with increased cyclin D1 expression, activation of cyclin-dependent kinases (Cdks), and phosphorylation of the retinoblastoma protein (pRb). We have utilized blocka...

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Bibliografische Detailangaben
Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Foster, James S., Henley, Donald C., Bukovsky, Antonin, Seth, Prem, Wimalasena, Jay
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2001
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86671/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11154267/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.3.794-810.2001
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