Multifaceted Regulation of Cell Cycle Progression by Estrogen: Regulation of Cdk Inhibitors and Cdc25A Independent of Cyclin D1-Cdk4 Function

Estrogens induce proliferation of estrogen receptor (ER)-positive MCF-7 breast cancer cells by stimulating G(1)/S transition associated with increased cyclin D1 expression, activation of cyclin-dependent kinases (Cdks), and phosphorylation of the retinoblastoma protein (pRb). We have utilized blocka...

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Bibliografiske detaljer
Main Authors: Foster, James S., Henley, Donald C., Bukovsky, Antonin, Seth, Prem, Wimalasena, Jay
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2001
Fag:
Cell Growth and Development
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC86671/
https://ncbi.nlm.nih.gov/pubmed/11154267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.3.794-810.2001
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