Involvement of Nucleotide Excision Repair in a Recombination-Independent and Error-Prone Pathway of DNA Interstrand Cross-Link Repair

DNA interstrand cross-links (ICLs) block the strand separation necessary for essential DNA functions such as transcription and replication and, hence, represent an important class of DNA lesion. Since both strands of the double helix are affected in cross-linked DNA, it is likely that conservative r...

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Main Authors: Wang, Xin, Peterson, Carolyn A., Zheng, Huyong, Nairn, Rodney S., Legerski, Randy J., Li, Lei
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2001
Assuntos:
DNA Dynamics and Chromosome Structure
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC86663/
https://ncbi.nlm.nih.gov/pubmed/11154259
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.3.713-720.2001
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