Loss of Orphan Receptor Germ Cell Nuclear Factor Function Results in Ectopic Development of the Tail Bud and a Novel Posterior Truncation

The dynamic embryonic expression of germ cell nuclear factor (GCNF), an orphan nuclear receptor, suggests that it may play an important role during early development. To determine the physiological role of GCNF, we have generated a targeted mutation of the GCNF gene in mice. Germ line mutation of th...

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Εκδόθηκε σε:	Mol Cell Biol
Κύριοι συγγραφείς:	Chung, Arthur C.-K., Katz, Deborah, Pereira, Fred A., Jackson, Kathy J., DeMayo, Francesco J., Cooney, Austin J., O'Malley, Bert W.
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Taylor & Francis 2001
Θέματα:	Mammalian Genetic Models with Minimal or Complex Phenotypes
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86646/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11134352/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/MCB.21.2.663-677.2001
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