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Loss of Orphan Receptor Germ Cell Nuclear Factor Function Results in Ectopic Development of the Tail Bud and a Novel Posterior Truncation

The dynamic embryonic expression of germ cell nuclear factor (GCNF), an orphan nuclear receptor, suggests that it may play an important role during early development. To determine the physiological role of GCNF, we have generated a targeted mutation of the GCNF gene in mice. Germ line mutation of th...

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Detalhes bibliográficos
Main Authors: Chung, Arthur C.-K., Katz, Deborah, Pereira, Fred A., Jackson, Kathy J., DeMayo, Francesco J., Cooney, Austin J., O'Malley, Bert W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC86646/
https://ncbi.nlm.nih.gov/pubmed/11134352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.2.663-677.2001
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