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Stimulation of CREB Binding Protein Nucleosomal Histone Acetyltransferase Activity by a Class of Transcriptional Activators

The transcriptional coactivator CREB binding protein (CBP) possesses intrinsic histone acetyltransferase (HAT) activity that is important for gene regulation. CBP binds to and cooperates with numerous nuclear factors to stimulate transcription, but it is unclear if these factors modulate CBP HAT act...

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Autori principali: Chen, Chi-Ju, Deng, Zhong, Kim, Alex Y., Blobel, Gerd A., Lieberman, Paul M.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2001
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC86604/
https://ncbi.nlm.nih.gov/pubmed/11134336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.21.2.476-487.2001
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