Novel Upf2p Orthologues Suggest a Functional Link between Translation Initiation and Nonsense Surveillance Complexes

Transcripts harboring premature signals for translation termination are recognized and rapidly degraded by eukaryotic cells through a pathway known as nonsense-mediated mRNA decay (NMD). In addition to protecting cells by preventing the translation of potentially deleterious truncated peptides, stud...

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Detalhes bibliográficos

Publicado no:	Mol Cell Biol
Principais autores:	Mendell, Joshua T., Medghalchi, Susan M., Lake, Ross G., Noensie, Erick N., Dietz, Harry C.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Taylor & Francis 2000
Assuntos:	Gene Expression
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86549/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073994/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.8944-8957.2000
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