Phosphorylation-Induced Dimerization of Interferon Regulatory Factor 7 Unmasks DNA Binding and a Bipartite Transactivation Domain

Interferon regulatory factor 7 (IRF7) is an interferon (IFN)-inducible transcription factor required for activation of a subset of IFN-α genes that are expressed with delayed kinetics following viral infection. IRF7 is synthesized as a latent protein and is posttranslationally modified by protein ph...

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Publié dans:	Mol Cell Biol
Auteurs principaux:	Marié, Isabelle, Smith, Eric, Prakash, Arun, Levy, David E.
Format:	Artigo
Langue:	Inglês
Publié:	Taylor & Francis 2000
Sujets:	Transcriptional Regulation
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86519/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073981/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.8803-8814.2000
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