Phosphorylation-Induced Dimerization of Interferon Regulatory Factor 7 Unmasks DNA Binding and a Bipartite Transactivation Domain

Interferon regulatory factor 7 (IRF7) is an interferon (IFN)-inducible transcription factor required for activation of a subset of IFN-α genes that are expressed with delayed kinetics following viral infection. IRF7 is synthesized as a latent protein and is posttranslationally modified by protein ph...

Full description

Saved in:
Bibliographic Details
Main Authors: Marié, Isabelle, Smith, Eric, Prakash, Arun, Levy, David E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC86519/
https://ncbi.nlm.nih.gov/pubmed/11073981
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items