Repression of c-myc Is Necessary but Not Sufficient for Terminal Differentiation of B Lymphocytes In Vitro
The importance of c-myc as a target of the Blimp-1 repressor has been studied in BCL-1 cells, in which Blimp-1 is sufficient to trigger terminal B-cell differentiation. Our data show that Blimp-1-dependent repression of c-myc is required for BCL-1 differentiation, since constitutive expression of c-...
Spremljeno u:
| Izdano u: | Mol Cell Biol |
|---|---|
| Glavni autori: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Taylor & Francis
2000
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86481/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.8684-8695.2000 |
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