Repression of c-myc Is Necessary but Not Sufficient for Terminal Differentiation of B Lymphocytes In Vitro

The importance of c-myc as a target of the Blimp-1 repressor has been studied in BCL-1 cells, in which Blimp-1 is sufficient to trigger terminal B-cell differentiation. Our data show that Blimp-1-dependent repression of c-myc is required for BCL-1 differentiation, since constitutive expression of c-...

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Pubblicato in:	Mol Cell Biol
Autori principali:	Lin, Kuo-I, Lin, Yi, Calame, Kathryn
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Taylor & Francis 2000
Soggetti:	Cell Growth and Development
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC86481/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11073970/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.23.8684-8695.2000
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