Identification and Characterization of an Activating TrkA Deletion Mutation in Acute Myeloid Leukemia

In this study, we utilized retroviral transfer of cDNA libraries in order to identify oncogenes that are expressed in acute myeloid leukemia (AML). From screens using two different cell types as targets for cellular transformation, a single cDNA encoding a variant of the TrkA protooncogene was isola...

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Bibliographic Details
Main Authors: Reuther, Gary W., Lambert, Que T., Caligiuri, Michael A., Der, Channing J.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Cell Growth and Development
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC86471/
https://ncbi.nlm.nih.gov/pubmed/11073967
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